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A General Approach for Receptor and Antibody-Targeted Detection of Native Proteins utilizing Split-Luciferase Reassembly

The direct detection of native proteins in heterogeneous solutions remains a challenging problem. Standard methodologies rely on a separation step to circumvent non-specific signal generation. We hypothesized that a simple and general method for the detection of native proteins in solution could be...

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Hlavní autoři: Stains, Cliff I., Furman, Jennifer L., Porter, Jason R., Rajagopal, Srivats, Li, Yuxing, Wyatt, Richard T., Ghosh, Indraneel
Médium: Artigo
Jazyk:Inglês
Vydáno: 2010
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2955838/
https://ncbi.nlm.nih.gov/pubmed/20681584
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/cb100143m
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