Oncogenic Role of the E3 Ubiquitin Ligase NEDD4-1, a PTEN Negative Regulator, in Non-Small-Cell Lung Carcinomas

Loss of the PTEN tumor suppressor gene occurs frequently in non-small-cell lung carcinoma (NSCLC), although neither genetic alterations nor epigenetic silencing are significant predictors of PTEN protein levels. Since recent reports implicated neural precursor cell expressed, developmentally down-re...

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Detalhes bibliográficos
Main Authors: Amodio, Nicola, Scrima, Marianna, Palaia, Lucia, Salman, Ali Naeem, Quintiero, Alfina, Franco, Renato, Botti, Gerardo, Pirozzi, Pino, Rocco, Gaetano, De Rosa, Nicla, Viglietto, Giuseppe
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Investigative Pathology 2010
Assuntos:
Regular Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2966817/
https://ncbi.nlm.nih.gov/pubmed/20889565
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2353/ajpath.2010.091075
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