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Ubiquitination of alpha-synuclein filaments by Nedd4 ligases
Alpha-synuclein can form beta-sheet filaments, the accumulation of which plays a key role in the development of Parkinson’s disease, dementia with Lewy bodies and multiple system atrophy. It has previously been shown that alpha-synuclein is a substrate for the HECT domain-containing ubiquitin ligase...
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| Pubblicato in: | PLoS One |
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| Autori principali: | , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Public Library of Science
2018
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6051637/ https://ncbi.nlm.nih.gov/pubmed/30021006 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0200763 |
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