Deletions of 16q in Wilms Tumors Localize to Blastemal-Anaplastic Cells and Are Associated with Reduced Expression of the IRXB Renal Tubulogenesis Gene Cluster

Wilms tumor is the most common pediatric renal neoplasm, but few molecular prognostic markers have been identified for this tumor. Somatic deletion in the long arm of chromosome 16 (16q) is known to predict a less favorable outcome in Wilms tumor, but the underlying molecular mechanisms are not know...

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Autors principals: Mengelbier, Linda Holmquist, Karlsson, Jenny, Lindgren, David, Øra, Ingrid, Isaksson, Margareth, Frigyesi, Ildiko, Frigyesi, Attila, Bras, Johannes, Sandstedt, Bengt, Gisselsson, David
Format: Artigo
Idioma:Inglês
Publicat: American Society for Investigative Pathology 2010
Matèries:
Regular Articles
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2966816/
https://ncbi.nlm.nih.gov/pubmed/20847289
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2353/ajpath.2010.100130
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