Deletions of 16q in Wilms Tumors Localize to Blastemal-Anaplastic Cells and Are Associated with Reduced Expression of the IRXB Renal Tubulogenesis Gene Cluster

Wilms tumor is the most common pediatric renal neoplasm, but few molecular prognostic markers have been identified for this tumor. Somatic deletion in the long arm of chromosome 16 (16q) is known to predict a less favorable outcome in Wilms tumor, but the underlying molecular mechanisms are not know...

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Detalhes bibliográficos
Main Authors: Mengelbier, Linda Holmquist, Karlsson, Jenny, Lindgren, David, Øra, Ingrid, Isaksson, Margareth, Frigyesi, Ildiko, Frigyesi, Attila, Bras, Johannes, Sandstedt, Bengt, Gisselsson, David
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Investigative Pathology 2010
Assuntos:
Regular Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2966816/
https://ncbi.nlm.nih.gov/pubmed/20847289
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2353/ajpath.2010.100130
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