Deletions of 16q in Wilms Tumors Localize to Blastemal-Anaplastic Cells and Are Associated with Reduced Expression of the IRXB Renal Tubulogenesis Gene Cluster

Wilms tumor is the most common pediatric renal neoplasm, but few molecular prognostic markers have been identified for this tumor. Somatic deletion in the long arm of chromosome 16 (16q) is known to predict a less favorable outcome in Wilms tumor, but the underlying molecular mechanisms are not know...

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Hlavní autoři: Mengelbier, Linda Holmquist, Karlsson, Jenny, Lindgren, David, Øra, Ingrid, Isaksson, Margareth, Frigyesi, Ildiko, Frigyesi, Attila, Bras, Johannes, Sandstedt, Bengt, Gisselsson, David
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Investigative Pathology 2010
Témata:
Regular Articles
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2966816/
https://ncbi.nlm.nih.gov/pubmed/20847289
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2353/ajpath.2010.100130
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