Wilms’ Tumor Blastemal Stem Cells Dedifferentiate to Propagate the Tumor Bulk

An open question remains in cancer stem cell (CSC) biology whether CSCs are by definition at the top of the differentiation hierarchy of the tumor. Wilms’ tumor (WT), composed of blastema and differentiated renal elements resembling the nephrogenic zone of the developing kidney, is a valuable model...

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Detalhes bibliográficos
Main Authors: Shukrun, Rachel, Pode-Shakked, Naomi, Pleniceanu, Oren, Omer, Dorit, Vax, Einav, Peer, Eyal, Pri-Chen, Sara, Jacob, Jasmine, Hu, Qianghua, Harari-Steinberg, Orit, Huff, Vicki, Dekel, Benjamin
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2014
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4110791/
https://ncbi.nlm.nih.gov/pubmed/25068119
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stemcr.2014.05.013
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