Wilms’ Tumor Blastemal Stem Cells Dedifferentiate to Propagate the Tumor Bulk

An open question remains in cancer stem cell (CSC) biology whether CSCs are by definition at the top of the differentiation hierarchy of the tumor. Wilms’ tumor (WT), composed of blastema and differentiated renal elements resembling the nephrogenic zone of the developing kidney, is a valuable model...

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Détails bibliographiques
Auteurs principaux: Shukrun, Rachel, Pode-Shakked, Naomi, Pleniceanu, Oren, Omer, Dorit, Vax, Einav, Peer, Eyal, Pri-Chen, Sara, Jacob, Jasmine, Hu, Qianghua, Harari-Steinberg, Orit, Huff, Vicki, Dekel, Benjamin
Format: Artigo
Langue:Inglês
Publié: Elsevier 2014
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4110791/
https://ncbi.nlm.nih.gov/pubmed/25068119
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stemcr.2014.05.013
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