Wilms’ Tumor Blastemal Stem Cells Dedifferentiate to Propagate the Tumor Bulk

An open question remains in cancer stem cell (CSC) biology whether CSCs are by definition at the top of the differentiation hierarchy of the tumor. Wilms’ tumor (WT), composed of blastema and differentiated renal elements resembling the nephrogenic zone of the developing kidney, is a valuable model...

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Bibliografische gegevens
Hoofdauteurs: Shukrun, Rachel, Pode-Shakked, Naomi, Pleniceanu, Oren, Omer, Dorit, Vax, Einav, Peer, Eyal, Pri-Chen, Sara, Jacob, Jasmine, Hu, Qianghua, Harari-Steinberg, Orit, Huff, Vicki, Dekel, Benjamin
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Elsevier 2014
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4110791/
https://ncbi.nlm.nih.gov/pubmed/25068119
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stemcr.2014.05.013
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