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Oligodendrocyte PTEN required for myelin and axonal integrity not remyelination
OBJECTIVE: Repair of myelin injury in multiple sclerosis may fail resulting in chronic demyelination, axonal loss and disease progression. As cellular pathways regulated by Phosphatase and tensin homologue deleted on chromosome 10 (PTEN; e.g., PI-3Kinase) have been reported to enhance axon regenerat...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2966537/ https://ncbi.nlm.nih.gov/pubmed/20853437 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ana.22090 |
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