Genetically Induced Adult Oligodendrocyte Cell Death Is Associated with Poor Myelin Clearance, Reduced Remyelination, and Axonal Damage

Loss of oligodendrocytes is a feature of many demyelinating diseases including multiple sclerosis. Here, we have established and characterized a novel model of genetically induced adult oligodendrocyte death. Specific primary loss of adult oligodendrocytes leads to a well defined and highly reproduc...

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Bibliographic Details
Published in:J Neurosci
Main Authors: Pohl, Hartmut B. F., Porcheri, Cristina, Mueggler, Thomas, Bachmann, Lukas C., Martino, Gianvito, Riethmacher, Dieter, Franklin, Robin J. M., Rudin, Markus, Suter, Ueli
Format: Artigo
Language:Inglês
Published: Society for Neuroscience 2011
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6632929/
https://ncbi.nlm.nih.gov/pubmed/21248132
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.5035-10.2011
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