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Prolonging hormone sensitivity in prostate cancer xenografts through dual inhibition of AR and mTOR
BACKGROUND: To determine the mechanisms associated with loss of androgen dependency and disease progression in prostate cancer (PCa), we investigated the relationship between the androgen receptor (AR) and mTOR pathways and the impact of inhibiting both pathways in androgen-dependent and castration-...
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| Главные авторы: | , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Nature Publishing Group
2010
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2965879/ https://ncbi.nlm.nih.gov/pubmed/20842117 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6605882 |
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