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Inhibitory effects of retinoic acid metabolism blocking agents (RAMBAs) on the growth of human prostate cancer cells and LNCaP prostate tumour xenografts in SCID mice
In recent studies, we have identified several highly potent all-trans-retinoic acid (ATRA) metabolism blocking agents (RAMBAs). On the basis of previous effects of liarozole (a first-generation RAMBA) on the catabolism of ATRA and on growth of rat Dunning R3227G prostate tumours, we assessed the eff...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
Nature Publishing Group
2006
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| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2361176/ https://ncbi.nlm.nih.gov/pubmed/16449997 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6602971 |
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