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Repeated probing of Southwestern blots using alkaline phosphatase stripping

Southwestern blotting is when a DNA sequence is used to probe DNA-binding proteins on an electrophoretic gel blot. It would be highly desirable to be able to probe a blot repeatedly with different DNA sequences. Alkaline phosphatase can remove 5′-phosphoryl groups from DNA and radiolabeled 5′-(32)P-...

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Main Authors: Jia, Yinshan, Jiang, Daifeng, Jarrett, Harry W.
格式: Artigo
語言:Inglês
出版: 2010
主題:
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC2964665/
https://ncbi.nlm.nih.gov/pubmed/20926088
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.chroma.2010.09.033
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