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Preparation of oligodeoxynucleotide-alkaline phosphatase conjugates and their use as hybridization probes.

Short synthetic oligonucleotides have been covalently cross-linked to alkaline phosphatase using the homobifunctional reagent disuccinimidyl suberate. The oligomers, twenty-one to twenty-six bases in length, are complementary to unique sequences found in herpes simplex virus, hepatitis B virus, Camp...

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Bibliographic Details
Main Authors: Jablonski, E, Moomaw, E W, Tullis, R H, Ruth, J L
Format: Artigo
Language:Inglês
Published: 1986
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC311625/
https://ncbi.nlm.nih.gov/pubmed/3748805
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