Hypoxia-induced in vivo sickling of transgenic mouse red cells.

To develop an animal model for sickle cell anemia, we have created transgenic mice that express a severe naturally occurring human sickling hemoglobin, Hb S Antilles. Due to its low solubility and oxygen affinity, Hb S Antilles has a greater propensity to cause red cell sickling than Hb S. To make t...

Полное описание

Сохранить в:
Библиографические подробности
Главные авторы: Rubin, E M, Witkowska, H E, Spangler, E, Curtin, P, Lubin, B H, Mohandas, N, Clift, S M
Формат: Artigo
Язык:Inglês
Опубликовано: 1991
Предметы:
Research Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC296354/
https://ncbi.nlm.nih.gov/pubmed/1991848
Метки: Добавить метку
Нет меток, Требуется 1-ая метка записи!

Схожие документы