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Effect of fetal hemoglobin on microvascular regulation in sickle transgenic-knockout mice

In sickle cell disease, intravascular sickling and attendant flow abnormalities underlie the chronic inflammation and vascular endothelial abnormalities. However, the relationship between sickling and vascular tone is not well understood. We hypothesized that sickling-induced vaso-occlusive events a...

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Détails bibliographiques
Auteurs principaux: Kaul, Dhananjay K., Liu, Xiao-du, Chang, Hee-Yoon, Nagel, Ronald L., Fabry, Mary E.
Format: Artigo
Langue:Inglês
Publié: American Society for Clinical Investigation 2004
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC522244/
https://ncbi.nlm.nih.gov/pubmed/15489961
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI200421633
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