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Effect of fetal hemoglobin on microvascular regulation in sickle transgenic-knockout mice

In sickle cell disease, intravascular sickling and attendant flow abnormalities underlie the chronic inflammation and vascular endothelial abnormalities. However, the relationship between sickling and vascular tone is not well understood. We hypothesized that sickling-induced vaso-occlusive events a...

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Detalhes bibliográficos
Main Authors: Kaul, Dhananjay K., Liu, Xiao-du, Chang, Hee-Yoon, Nagel, Ronald L., Fabry, Mary E.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2004
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC522244/
https://ncbi.nlm.nih.gov/pubmed/15489961
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI200421633
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