Arachidonic Acid-metabolizing Cytochrome P450 Enzymes Are Targets of ω-3 Fatty Acids

Eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA) protect against cardiovascular disease by largely unknown mechanisms. We tested the hypothesis that EPA and DHA may compete with arachidonic acid (AA) for the conversion by cytochrome P450 (CYP) enzymes, resulting in the formation of alterna...

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Detalles Bibliográficos
Main Authors: Arnold, Cosima, Markovic, Marija, Blossey, Katrin, Wallukat, Gerd, Fischer, Robert, Dechend, Ralf, Konkel, Anne, von Schacky, Clemens, Luft, Friedrich C., Muller, Dominik N., Rothe, Michael, Schunck, Wolf-Hagen
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Biochemistry and Molecular Biology 2010
Assuntos:
Enzymology
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2963419/
https://ncbi.nlm.nih.gov/pubmed/20732876
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.118406
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