Dietary omega-3 fatty acids modulate the eicosanoid profile in man primarily via the CYP-epoxygenase pathway

Cytochrome P450 (CYP)-dependent metabolites of arachidonic acid (AA) contribute to the regulation of cardiovascular function. CYP enzymes also accept EPA and DHA to yield more potent vasodilatory and potentially anti-arrhythmic metabolites, suggesting that the endogenous CYP-eicosanoid profile can b...

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Dettagli Bibliografici
Autori principali: Fischer, Robert, Konkel, Anne, Mehling, Heidrun, Blossey, Katrin, Gapelyuk, Andrej, Wessel, Niels, von Schacky, Clemens, Dechend, Ralf, Muller, Dominik N., Rothe, Michael, Luft, Friedrich C., Weylandt, Karsten, Schunck, Wolf-Hagen
Natura: Artigo
Lingua:Inglês
Pubblicazione: The American Society for Biochemistry and Molecular Biology 2014
Soggetti:
Patient-Oriented and Epidemiological Research
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4031946/
https://ncbi.nlm.nih.gov/pubmed/24634501
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.M047357
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