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Mechanism of E1-E2 Interaction for the Inhibition of Ubl Adenylation
Conjugates of ubiquitin or its homologues to other proteins occur by strictly ordered steps with ordered addition of substrates for each step. High concentrations of E2 were shown to inhibit the formation of E2∼Ubl thioester and Ubl∼target conjugates. We investigated the mechanism of such inhibitory...
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| 主要な著者: | , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
American Society for Biochemistry and Molecular Biology
2010
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2963334/ https://ncbi.nlm.nih.gov/pubmed/20682785 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.135582 |
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