Cargando...

Mechanism of E1-E2 Interaction for the Inhibition of Ubl Adenylation

Conjugates of ubiquitin or its homologues to other proteins occur by strictly ordered steps with ordered addition of substrates for each step. High concentrations of E2 were shown to inhibit the formation of E2∼Ubl thioester and Ubl∼target conjugates. We investigated the mechanism of such inhibitory...

Descrición completa

Gardado en:
Detalles Bibliográficos
Main Authors: Wang, Jianghai, Cai, Sheng, Chen, Yuan
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Biochemistry and Molecular Biology 2010
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2963334/
https://ncbi.nlm.nih.gov/pubmed/20682785
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.135582
Tags: Engadir etiqueta
Sen Etiquetas, Sexa o primeiro en etiquetar este rexistro!