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CD4(+) T cells Are Not Required for the Induction of Dengue Virus-Specific CD8(+) T cell or Antibody Responses but Contribute to Protection After Vaccination
The contribution of T cells to the host response to dengue virus (DENV) infection is not well understood. We previously demonstrated a protective role for CD8(+) T cells during primary DENV infection using a mouse-passaged DENV strain and IFN-α/βR(−/−) C57BL/6 mice, which are susceptible to DENV inf...
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| Главные авторы: | , , , , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2010
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2962919/ https://ncbi.nlm.nih.gov/pubmed/20870934 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1001709 |
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