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Gamma Interferon (IFN-γ) Receptor Restricts Systemic Dengue Virus Replication and Prevents Paralysis in IFN-α/β Receptor-Deficient Mice

We previously reported that mice lacking alpha/beta and gamma interferon receptors (IFN-α/βR and -γR) uniformly exhibit paralysis following infection with the dengue virus (DENV) clinical isolate PL046, while only a subset of mice lacking the IFN-γR alone and virtually no mice lacking the IFN-α/βR a...

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Detalhes bibliográficos
Main Authors: Prestwood, Tyler R., Morar, Malika M., Zellweger, Raphaël M., Miller, Robyn, May, Monica M., Yauch, Lauren E., Lada, Steven M., Shresta, Sujan
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3497655/
https://ncbi.nlm.nih.gov/pubmed/22973027
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.06743-11
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