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Trafficking and Replication Patterns Reveal Splenic Macrophages as Major Targets of Dengue Virus in Mice

Human postmortem studies of natural dengue virus (DENV) infection have reported systemically distributed viral antigen. Although it is widely accepted that DENV infects mononuclear phagocytes, the sequence in which specific tissues and cell types are targeted remains uncharacterized. We previously r...

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Autores principales: Prestwood, Tyler R., May, Monica M., Plummer, Emily M., Morar, Malika M., Yauch, Lauren E., Shresta, Sujan
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology 2012
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3486461/
https://ncbi.nlm.nih.gov/pubmed/22933295
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00375-12
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