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Cardif-Mediated Signaling Controls the Initial Innate Response to Dengue Virus In Vivo
The role of Cardif-dependent signaling in controlling dengue virus (DENV) infection and regulating type I interferon (IFN) production in vivo was examined in Cardif-deficient mice. DENV RNA levels were significantly elevated in both the serum and lymphoid tissues of Cardif(−/−) mice at early times c...
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| Autores principales: | , , , , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
American Society for Microbiology (ASM)
2009
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2715757/ https://ncbi.nlm.nih.gov/pubmed/19494017 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00365-09 |
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