STAT2 Mediates Innate Immunity to Dengue Virus in the Absence of STAT1 via the Type I Interferon Receptor

Dengue virus (DENV) is a mosquito-borne flavivirus, and symptoms of infection range from asymptomatic to the severe dengue hemorrhagic fever/dengue shock syndrome (DHF/DSS). High viral loads correlate with disease severity, and both type I & II interferons (IFNs) are crucial for controlling vira...

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Detalhes bibliográficos
Main Authors: Perry, Stuart T., Buck, Michael D., Lada, Steven M., Schindler, Christian, Shresta, Sujan
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2011
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3040673/
https://ncbi.nlm.nih.gov/pubmed/21379341
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1001297
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