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Response to interferons and antibacterial innate immunity in the absence of tyrosine‐phosphorylated STAT1

Signal transducer and activator of transcription 1 (STAT1) plays a pivotal role in the innate immune system by directing the transcriptional response to interferons (IFNs). STAT1 is activated by Janus kinase (JAK)‐mediated phosphorylation of Y701. To determine whether STAT1 contributes to cellular r...

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Detalhes bibliográficos
Publicado no:EMBO Rep
Main Authors: Majoros, Andrea, Platanitis, Ekaterini, Szappanos, Daniel, Cheon, HyeonJoo, Vogl, Claus, Shukla, Priyank, Stark, George R, Sexl, Veronika, Schreiber, Robert, Schindler, Christian, Müller, Mathias, Decker, Thomas
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4772975/
https://ncbi.nlm.nih.gov/pubmed/26882544
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embr.201540726
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