Canonical and Non-Canonical Aspects of JAK–STAT Signaling: Lessons from Interferons for Cytokine Responses

Janus kinase (JAK)–signal transducer and activator of transcription (STAT) signal transduction mediates cytokine responses. Canonical signaling is based on STAT tyrosine phosphorylation by activated JAKs. Downstream of interferon (IFN) receptors, activated JAKs cause the formation of the transcripti...

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Dades bibliogràfiques
Publicat a:Front Immunol
Autors principals: Majoros, Andrea, Platanitis, Ekaterini, Kernbauer-Hölzl, Elisabeth, Rosebrock, Felix, Müller, Mathias, Decker, Thomas
Format: Artigo
Idioma:Inglês
Publicat: Frontiers Media S.A. 2017
Matèries:
Immunology
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5266721/
https://ncbi.nlm.nih.gov/pubmed/28184222
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2017.00029
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