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The regulation of inflammation by interferons and their STATs

Interferons (IFN) are subdivided into type I IFN (IFN-I, here synonymous with IFN-α/β), type II (IFN-γ) and type III IFN (IFN-III/IFN-λ) that reprogram nuclear gene expression through STATs 1 and 2 by forming STAT1 dimers (mainly IFN-γ) or the ISGF3 complex, a STAT1-STAT2-IRF9 heterotrimer (IFN-I an...

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Autori principali: Rauch, Isabella, Müller, Mathias, Decker, Thomas
Natura: Artigo
Lingua:Inglês
Pubblicazione: Landes Bioscience 2013
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3670275/
https://ncbi.nlm.nih.gov/pubmed/24058799
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/jkst.23820
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