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Mouse Models to Study Dengue Virus Immunology and Pathogenesis

The development of a compelling murine model of dengue virus (DENV) infection has been challenging, because DENV clinical isolates do not readily replicate or cause pathology in immunocompetent mice. However, research using immunocompromised mice and/or mouse-adapted viruses allows investigation of...

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Detalhes bibliográficos
Main Authors: Zellweger, Raphaël M., Shresta, Sujan
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3989707/
https://ncbi.nlm.nih.gov/pubmed/24782859
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2014.00151
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