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CD4(+) T cells Are Not Required for the Induction of Dengue Virus-Specific CD8(+) T cell or Antibody Responses but Contribute to Protection After Vaccination

The contribution of T cells to the host response to dengue virus (DENV) infection is not well understood. We previously demonstrated a protective role for CD8(+) T cells during primary DENV infection using a mouse-passaged DENV strain and IFN-α/βR(−/−) C57BL/6 mice, which are susceptible to DENV inf...

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Bibliografiska uppgifter
Huvudupphovsmän: Yauch, Lauren E., Prestwood, Tyler R., May, Monica M., Morar, Malika M., Zellweger, Raphaël M., Peters, Bjoern, Sette, Alessandro, Shresta, Sujan
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2010
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC2962919/
https://ncbi.nlm.nih.gov/pubmed/20870934
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1001709
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