Valerenic acid derivatives as novel subunit-selective GABA(A) receptor ligands –in vitro and in vivo characterization

BACKGROUND AND PURPOSE: Subunit-specific modulators of γ-aminobutyric acid (GABA) type A (GABA(A)) receptors can help to assess the physiological function of receptors with different subunit composition and also provide the basis for the development of new drugs. Valerenic acid (VA) was recently ide...

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Hlavní autoři: Khom, S, Strommer, B, Ramharter, J, Schwarz, T, Schwarzer, C, Erker, T, Ecker, GF, Mulzer, J, Hering, S
Médium: Artigo
Jazyk:Inglês
Vydáno: Blackwell Publishing Ltd 2010
Témata:
Research Papers
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2962817/
https://ncbi.nlm.nih.gov/pubmed/20718740
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1476-5381.2010.00865.x
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