Valerenic acid derivatives as novel subunit-selective GABA(A) receptor ligands –in vitro and in vivo characterization

BACKGROUND AND PURPOSE: Subunit-specific modulators of γ-aminobutyric acid (GABA) type A (GABA(A)) receptors can help to assess the physiological function of receptors with different subunit composition and also provide the basis for the development of new drugs. Valerenic acid (VA) was recently ide...

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Detalhes bibliográficos
Main Authors: Khom, S, Strommer, B, Ramharter, J, Schwarz, T, Schwarzer, C, Erker, T, Ecker, GF, Mulzer, J, Hering, S
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Publishing Ltd 2010
Assuntos:
Research Papers
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2962817/
https://ncbi.nlm.nih.gov/pubmed/20718740
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1476-5381.2010.00865.x
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