Chargement en cours...
Targeting HER2: A report on the in vitro and in vivo pre-clinical data supporting trastuzumab as a radioimmunoconjugate for clinical trials
The potential of the HER2-targeting antibody trastuzumab as a radioimmunoconjugate useful for both imaging and therapy was investigated. Conjugation of trastuzumab with the acyclic bifunctional chelator CHX-A″-DTPA yielded a chelate:protein ratio of 3.4 ± 0.3; the immunoreactivity of the antibody un...
Enregistré dans:
| Auteurs principaux: | , , , , , , |
|---|---|
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Landes Bioscience
2010
|
| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2958576/ https://ncbi.nlm.nih.gov/pubmed/20716957 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/mabs.2.5.13054 |
| Tags: |
Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!
|