PET imaging of HER1-expressing xenografts in mice with (86)Y-CHX-A”-DTPA-cetuximab

Cetuximab is a recombinant, human/mouse chimeric IgG(1), monoclonal antibody (mAb) that binds to the epidermal growth factor receptor (EGFR/HER1). Cetuximab is approved for the treatment of patients with HER1-expressing metastatic colorectal cancer. Limitations in currently reported radiolabeled cet...

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Autors principals: Nayak, Tapan K., Regino, Celeste A.S., Wong, Karen J., Milenic, Diane E., Garmestani, Kayhan, Baidoo, Kwamena E., Szajek, Lawrence P., Brechbiel, Martin W.
Format: Artigo
Idioma:Inglês
Publicat: 2010
Matèries:
Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2891840/
https://ncbi.nlm.nih.gov/pubmed/20155263
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00259-009-1370-z
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