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PET imaging of tumor angiogenesis in mice with VEGF-A targeted (86)Y-CHX-A″-DTPA-bevacizumab

Bevacizumab is a humanized monoclonal antibody that binds to tumor-secreted VEGF-A and inhibits tumor angiogenesis. In 2004, the antibody was approved by the United States FDA for the treatment of metastatic colorectal carcinoma in combination with chemotherapy. This report describes the preclinical...

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Autors principals: Nayak, Tapan K., Garmestani, Kayhan, Baidoo, Kwamena E., Milenic, Diane E., Brechbiel, Martin W.
Format: Artigo
Idioma:Inglês
Publicat: 2011
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2939172/
https://ncbi.nlm.nih.gov/pubmed/20473899
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ijc.25409
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