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PET imaging of tumor angiogenesis in mice with VEGF-A targeted (86)Y-CHX-A″-DTPA-bevacizumab

Bevacizumab is a humanized monoclonal antibody that binds to tumor-secreted VEGF-A and inhibits tumor angiogenesis. In 2004, the antibody was approved by the United States FDA for the treatment of metastatic colorectal carcinoma in combination with chemotherapy. This report describes the preclinical...

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Bibliografiska uppgifter
Huvudupphovsmän: Nayak, Tapan K., Garmestani, Kayhan, Baidoo, Kwamena E., Milenic, Diane E., Brechbiel, Martin W.
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2011
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Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC2939172/
https://ncbi.nlm.nih.gov/pubmed/20473899
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ijc.25409
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