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HER1-Targeted (86)Y-Panitumumab Possesses Superior Targeting Characteristics than (86)Y-Cetuximab for PET Imaging of Human Malignant Mesothelioma Tumors Xenografts

Malignant mesothelioma (MM), a rare form of cancer is often associated with previous exposure to fibrous minerals, such as asbestos. Asbestos exposure increases HER1-activity and expression in pre-clinical models. Additionally, HER1 over-expression is observed in the majority of MM cases. In this st...

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Detalhes bibliográficos
Main Authors: Nayak, Tapan K., Garmestani, Kayhan, Milenic, Diane E., Baidoo, Kwamena E., Brechbiel, Martin W.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3064677/
https://ncbi.nlm.nih.gov/pubmed/21464917
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0018198
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