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Intratumoral Heterogeneity of HER-2 Gene Amplification and Protein Overexpression in Breast Cancer
We report a case of a patient with invasive breast carcinoma which demonstrated HER-2 gene amplification on core biopsy, who relapsed while on adjuvant Trastuzumab therapy following her mastectomy and ultimately died 15 months after diagnosis. Surprisingly, analysis of multiple metastases harvested...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2958099/ https://ncbi.nlm.nih.gov/pubmed/20338615 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.humpath.2009.10.022 |
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