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High-content, cell-by-cell assessment of HER2 overexpression and amplification: a tool for intratumoral heterogeneity detection in breast cancer
Immunohistochemistry and fluorescence in situ hybridization are the two standard methods for Human Epidermal Growth Factor Receptor 2 (HER2) assessment. However, they have severe limitations to assess quantitatively intratumoral heterogeneity (ITH) when multiple subclones of tumor cells co-exist. We...
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| Publicado no: | Lab Invest |
|---|---|
| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6522386/ https://ncbi.nlm.nih.gov/pubmed/30659272 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41374-018-0172-y |
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