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High-content, cell-by-cell assessment of HER2 overexpression and amplification: a tool for intratumoral heterogeneity detection in breast cancer

Immunohistochemistry and fluorescence in situ hybridization are the two standard methods for Human Epidermal Growth Factor Receptor 2 (HER2) assessment. However, they have severe limitations to assess quantitatively intratumoral heterogeneity (ITH) when multiple subclones of tumor cells co-exist. We...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Lab Invest
Prif Awduron: Nguyen, Huu Tuan, Migliozzi, Daniel, Bisig, Bettina, de Leval, Laurence, Gijs, Martin A.M.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2019
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC6522386/
https://ncbi.nlm.nih.gov/pubmed/30659272
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41374-018-0172-y
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