Adverse Prognostic Impact of Intratumor Heterogeneous HER2 Gene Amplification in Patients With Esophageal Adenocarcinoma

PURPOSE: There is increasing recognition of the existence of intratumoral heterogeneity of the human epidermal growth factor receptor (HER2), which affects interpretation of HER2 positivity in clinical practice and may have implications for patient prognosis and treatment. We determined the frequenc...

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Detalhes bibliográficos
Principais autores: Yoon, Harry H., Shi, Qian, Sukov, William R., Lewis, Mark A., Sattler, Christopher A., Wiktor, Anne E., Wu, Tsung-Teh, Diasio, Robert B., Jenkins, Robert B., Sinicrope, Frank A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Clinical Oncology 2012
Assuntos:
Original Reports
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3675687/
https://ncbi.nlm.nih.gov/pubmed/22987085
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1200/JCO.2012.43.1890
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