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Combining fluorescence-based image segmentation and automated microfluidics for ultrafast cell-by-cell assessment of biomarkers for HER2-type breast carcinoma

Immunohistochemistry (IHC) is one of the main clinical techniques for biomarker assessment on tissue biopsies. It consists in chromogenic labeling with specific antibodies, followed by optical imaging, and it is used for diagnosis and therapeutic targeting. A well-known drawback of IHC is its limite...

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Detalhes bibliográficos
Publicado no:J Biomed Opt
Main Authors: Migliozzi, Daniel, Nguyen, Huu T., Gijs, Martin A. M.
Formato: Artigo
Idioma:Inglês
Publicado em: Society of Photo-Optical Instrumentation Engineers 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6987647/
https://ncbi.nlm.nih.gov/pubmed/30484294
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1117/1.JBO.24.2.021204
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