HER2 intratumoral heterogeneity analyses by concurrent HER2 gene and protein assessment for the prognosis of HER2 negative invasive breast cancer patients

HER2 gene-protein assay (GPA) is a new method for the simultaneous evaluation of HER2 immunohistochemistry (IHC) and HER2 dual in situ hybridization (DISH) on single tissue sections of breast cancer. We investigated the presence of HER2 gene and protein discrepancy and HER2-heterogeneity using HER2-...

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Bibliographic Details
Published in:Breast Cancer Res Treat
Main Authors: Kurozumi, Sasagu, Padilla, Mary, Kurosumi, Masafumi, Matsumoto, Hiroshi, Inoue, Kenichi, Horiguchi, Jun, Takeyoshi, Izumi, Oyama, Tetsunari, Ranger-Moore, Jim, Allred, D. Craig, Dennis, Eslie, Nitta, Hiroaki
Format: Artigo
Language:Inglês
Published: Springer US 2016
Subjects:
Clinical Trial
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4937084/
https://ncbi.nlm.nih.gov/pubmed/27318853
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10549-016-3856-2
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