HER2 intratumoral heterogeneity analyses by concurrent HER2 gene and protein assessment for the prognosis of HER2 negative invasive breast cancer patients

HER2 gene-protein assay (GPA) is a new method for the simultaneous evaluation of HER2 immunohistochemistry (IHC) and HER2 dual in situ hybridization (DISH) on single tissue sections of breast cancer. We investigated the presence of HER2 gene and protein discrepancy and HER2-heterogeneity using HER2-...

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Enregistré dans:
Détails bibliographiques
Publié dans:Breast Cancer Res Treat
Auteurs principaux: Kurozumi, Sasagu, Padilla, Mary, Kurosumi, Masafumi, Matsumoto, Hiroshi, Inoue, Kenichi, Horiguchi, Jun, Takeyoshi, Izumi, Oyama, Tetsunari, Ranger-Moore, Jim, Allred, D. Craig, Dennis, Eslie, Nitta, Hiroaki
Format: Artigo
Langue:Inglês
Publié: Springer US 2016
Sujets:
Clinical Trial
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4937084/
https://ncbi.nlm.nih.gov/pubmed/27318853
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10549-016-3856-2
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