ER, PgR, Ki67, p27(Kip1), and histological grade as predictors of pathological complete response in patients with HER2-positive breast cancer receiving neoadjuvant chemotherapy using taxanes followed by fluorouracil, epirubicin, and cyclophosphamide concomitant with trastuzumab

BACKGROUND: Neoadjuvant chemotherapy (NAC) with taxanes followed by fluorouracil, epirubicin, and cyclophosphamide (FEC), and concurrent trastuzumab is a potent regimen for HER2 over-expressing breast cancer. A high pathological complete response (pCR) rate has been achieved using this regimen; howe...

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Bibliografske podrobnosti
izdano v:BMC Cancer
Main Authors: Kurozumi, Sasagu, Inoue, Kenichi, Takei, Hiroyuki, Matsumoto, Hiroshi, Kurosumi, Masafumi, Horiguchi, Jun, Takeyoshi, Izumi, Oyama, Tetsunari
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2015
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4562359/
https://ncbi.nlm.nih.gov/pubmed/26345461
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12885-015-1641-y
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