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Sin1-mTORC2 suppresses rag and il7r gene expression through Akt2 in B cells
Mammalian target of rapamycin (mTOR) is an important mediator of phosphoinositol-3-kinase (PI3K) signaling. PI3K signaling regulates B cell development, homeostasis and immune responses. However, the function and molecular mechanism of mTOR mediated PI3K signaling in B cells has not been fully eluci...
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| Hauptverfasser: | , , , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2010
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2957800/ https://ncbi.nlm.nih.gov/pubmed/20705244 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2010.07.031 |
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