mTORC2 can associate with ribosomes to promote cotranslational phosphorylation and stability of nascent Akt polypeptide

The mechanisms that couple translation and protein processing are poorly understood in higher eukaryotes. Although mammalian target of rapamycin (mTOR) complex 1 (mTORC1) controls translation initiation, the function of mTORC2 in protein synthesis remains to be defined. In this study, we find that m...

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Hlavní autoři: Oh, Won Jun, Wu, Chang -chih, Kim, Sung Jin, Facchinetti, Valeria, Julien, Louis -André, Finlan, Monica, Roux, Philippe P, Su, Bing, Jacinto, Estela
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group 2010
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3020639/
https://ncbi.nlm.nih.gov/pubmed/21045808
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2010.271
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