mTORC2 can associate with ribosomes to promote cotranslational phosphorylation and stability of nascent Akt polypeptide

The mechanisms that couple translation and protein processing are poorly understood in higher eukaryotes. Although mammalian target of rapamycin (mTOR) complex 1 (mTORC1) controls translation initiation, the function of mTORC2 in protein synthesis remains to be defined. In this study, we find that m...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Hauptverfasser: Oh, Won Jun, Wu, Chang -chih, Kim, Sung Jin, Facchinetti, Valeria, Julien, Louis -André, Finlan, Monica, Roux, Philippe P, Su, Bing, Jacinto, Estela
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group 2010
Schlagworte:
Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3020639/
https://ncbi.nlm.nih.gov/pubmed/21045808
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2010.271
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!

Ähnliche Einträge