Epigenetic antagonism between Polycomb and SWI/SNF complexes during oncogenic transformation

Epigenetic alterations have been increasingly implicated in oncogenesis. Analysis of Drosophila mutants suggests that Polycomb and SWI/SNF complexes can serve antagonistic developmental roles. However, the relevance of this relationship to human disease is unclear. Here we have investigated function...

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Autors principals: Wilson, Boris G., Wang, Xi, Shen, Xiaohua, McKenna, Elizabeth S., Lemieux, Madeleine E., Cho, Yoon-Jae, Koellhoffer, Edward C., Pomeroy, Scott L., Orkin, Stuart H., Roberts, Charles W. M.
Format: Artigo
Idioma:Inglês
Publicat: 2010
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2957473/
https://ncbi.nlm.nih.gov/pubmed/20951942
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ccr.2010.09.006
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